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Biochemistry and Molecular Biology - Circadian Rhythms

Reference: JOB001
Location: Houston, TX
Employer: McGovern Medical School
Contact: Jake Chen, Ph.D.

Postdoctoral Fellow Positions at UT Health Science Center at Houston, TX, USA

Two federally-funded, full-time postdoctoral fellow positions are immediately available in the Department of Biochemistry and Molecular Biology at the University of Texas Health Science Center at Houston, USA.

The major research interests of our lab ( ) include circadian rhythms, metabolic aging and neurodegenerative diseases. In one major area of research, we previously identified clock-modulating compounds and demonstrated a role of circadian enhancement against metabolic disease and aging (Proc Natl Acad Sci U S A. 2012, 109:101; Cell Metab. 2016, 23:610; Nat Commun. 2019, 10:3923). Moving forward, we aim to deepen our investigation into the regulatory function of circadian rhythms (including sleep cycles) in aging and age-related diseases such as Alzheimer’s Disease. We will employ an integrative approach, combining molecular/cellular methodologies, mouse models, and unique pharmacological reagents. Circadian regulation in aging is an exciting new field, and success in these studies will have profound basic and translational impact.

Highly motivated candidates with a Ph.D. or an equivalent degree, preferably recently obtained, are encouraged to apply. The ideal candidate should have a demonstrated publication record and solid background in one or more of the following areas, including molecular/cell biology, mouse models and/or neurodegenerative diseases. However, all candidates will be considered. Competitive salary/benefits in line with NIH standards will be offered based on qualification.

The successful applicant will be working in a highly active research department at McGovern Medical School located within the renowned Texas Medical Center (TMC). The city of Houston also offers a comfortable lifestyle and ample career opportunities. To apply, please email a cover letter, CV, and names and contact information of three referees to Prof. Jake Chen (

UTHealth is committed to providing equal opportunity in all employment-related activities without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, gender identity or expression, veteran status or any other basis prohibited by law or university policy. Reasonable accommodation, based on disability or religious observances, will be considered in accordance with applicable law and UTHealth policy. The University maintains affirmative action programs with respect to women, minorities, individuals with disabilities, and eligible veterans in accordance with applicable law.

Contact's Phone Number: (713) 500-6284
Job Type: Full-time

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